NM23 as a prognostic biomarker in ovarian serous carcinoma
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چکیده
منابع مشابه
Prognostic Values of Estrogen and Progesterone Expression Receptors in Ovarian Papillary Serous Carcinoma
Background and Objectives: Presence of steroid hormone receptors (estrogen and progesterone) in the tumor tissues of various organs correlates with response to therapy and prognosis. Since their role in ovarian cancer is still controversial, in this study we investigated the expression and prognostic value of the estrogen receptor (ER) and progesterone receptors (PR) in ovarian papillary ser...
متن کاملc-erbB-2, p53, and nm23 proteins as prognostic factors in patients with epithelial ovarian carcinoma.
AIM To demonstrate immunohistochemical expression of p53, c-erbB-2, and nm23 proteins in ovarian cancer and to establish their correlation with such predictive factors as clinical stage, grade, and vascular invasion. The effect of protein overexpression on patients' overall survival was also assessed. METHOD We performed immunohistochemical analysis of formalin-fixed, paraffin-embedded specim...
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High-throughput genomic technologies have identified biomarkers and potential therapeutic targets for ovarian cancer. Comprehensive functional validation studies of the biological and clinical implications of these biomarkers are needed to advance them toward clinical use. Amplification of chromosomal region 5q31-5q35.3 has been used to predict poor prognosis in patients with advanced stage, hi...
متن کاملprognostic values of estrogen and progesterone expression receptors in ovarian papillary serous carcinoma
background and objectives: presence of steroid hormone receptors (estrogen and progesterone) in the tumor tissues of various organs correlates with response to therapy and prognosis. since their role in ovarian cancer is still controversial, in this study we investigated the expression and prognostic value of the estrogen receptor (er) and progesterone receptors (pr) in ovarian papillary serous...
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Background:Diagnosis of ovarian mass during pregnancy may be postponed because they may mimic physiological signs of pregnancy. Ovarian masses can lead to complications such as overgrowth, torsion or cyst rupture. Therefore, to inform health providers concerning symptoms, safe diagnostic methods and proper management seem appropriate. Case report: A 19-year-old primigravida was presented to our...
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ژورنال
عنوان ژورنال: Modern Pathology
سال: 2008
ISSN: 0893-3952,1530-0285
DOI: 10.1038/modpathol.2008.64